Notice of Retraction<BR>Aquatic Predicted No-Effect Concentration (PNEC) Derivation for Perfluorooctane Sulfonic Acid (PFOA)


Perfluorooctanoic acid (PFOA), the representative perfluorinated surfactant, is an anthropogenic pollutant detected in various environmental matrices. Little is known regarding its safe thresholds to the aquatic ecosystem. Predicted no-effect concentrations (PNECs) for PFOA were derived based on the measured/predicted chronic/acute toxicity data. The interspecies correlation estimation (ICE) program and final acute-to-chronic ratio (FACR) were applied to investigate their capability for the derivation of PNEC. The recommended aquatic toxicity thresholds for PFOA are in the range of 0.30 ~ 8.48 mg/L. The ICE-based species sensitivity distribution (SSD) method has certain potential for the derivation of PNEC especially when toxicity data are limited.


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